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Valve

Pathology

Murmur

Best Site for Auscultation

Optimal Position

SAMPLE SOUND

Aortic Valve

Aortic stenosis

Systolic ejection murmur (crescendo-decrescendo)

Right second intercostal space (aortic area)

Sitting, leaning forward, after exhaling

/uploads/278/2025/Mar/04/aortic sten.mp3

 

Aortic regurgitation

Diastolic decrescendo murmur

Left sternal border (3rd-4th intercostal spaces)

Sitting, leaning forward, after exhaling

/uploads/278/2025/Mar/04/aortic reg.mp3

Mitral Valve

Mitral stenosis

Diastolic rumbling murmur with opening snap

Apex (left 5th intercostal space, midclavicular line)

Left lateral decubitus

/uploads/278/2025/Mar/04/mitral sten.mp3

 

Mitral regurgitation

Holosystolic murmur

Apex, radiating to axilla

Left lateral decubitus

/uploads/278/2025/Mar/04/mitral reg.mp3

Pulmonary Valve

Pulmonary stenosis

Systolic ejection murmur

Left second intercostal space (pulmonic area)

Sitting upright

/uploads/278/pulm sten.mp3

 

Pulmonary regurgitation

Early diastolic murmur

Left upper sternal border

Sitting, leaning forward

/uploads/278/2025/Mar/04/pulm reg.mp3

Tricuspid Valve

Tricuspid stenosis

Mid-diastolic murmur

Left lower sternal border

Deep inspiration

 

Tricuspid regurgitation

Holosystolic murmur

Left lower sternal border

Deep inspiration

/uploads/278/tricus reg.mp3

 

 

 

 

 

 

 

Congenital Anomaly

Pathology

Murmur

Best Site for Auscultation

Optimal Position

SAMPLE SOUND

Atrial Septal Defect (ASD)

Left-to-right shunt across atrial septum

Systolic ejection murmur + fixed split S2

Left upper sternal border (pulmonic area)

Supine or sitting upright

/uploads/278/2025/Mar/04/ASD.mp3

Ventricular Septal Defect (VSD)

Left-to-right shunt across ventricular septum

Harsh holosystolic murmur

Left lower sternal border

Supine

/uploads/278/VSD.mp3

 

Patent Ductus Arteriosus (PDA)

Persistent ductus arteriosus

Continuous "machinery-like" murmur

Left infraclavicular area

Supine or sitting upright

/uploads/278/PDA _syst.mp3

Tetralogy of Fallot (TOF)

Right ventricular outflow obstruction, VSD, overriding aorta, RVH

Harsh systolic ejection murmur

Left upper sternal border

Squatting may reduce murmur intensity

 

Coarctation of the Aorta

Narrowing of aortic arch

Systolic murmur, often with radiation to the back

Left infraclavicular area and back

Sitting, leaning forward

/uploads/278/Coarctation aorta.mp3

Transposition of the Great Arteries (TGA)

Parallel circulation with possible VSD or PDA

No significant murmur unless associated defects present

Variable, depends on associated defects

Supine

 

 

Tricuspid Atresia

Hypoplastic right ventricle with ASD/VSD

Holosystolic murmur (if VSD present)

Left lower sternal border

Supine

 

Total Anomalous Pulmonary Venous Return (TAPVR)

Pulmonary veins drain into right atrium

Systolic ejection murmur

Left upper sternal border

Supine

/uploads/278/2025/Mar/04/TAPVR.mp3

Ebstein's Anomaly

Apical displacement of tricuspid valve

Holosystolic murmur of tricuspid regurgitation

Left lower sternal border

Supine, intensified with deep inspiration

 

 

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